| 16.10.2021 | 18:00 | Dürener TV II | Brühler TV | 0:3 (16:25, 17:25, 16:25) |
| 16.10.2021 | 19:00 | SSF Fortuna Bonn | PTSV Aachen II | 1:3 (23:25, 25:21, 19:25, 20:25) |
| 21.10.2021 | 20:00 | TSV Germania Windeck | FCJ Köln II | 3:1 (25:22, 22:25, 25:13, 25:18) |
| 23.10.2021 | 19:00 | Brühler TV | SSF Fortuna Bonn | 3:0 (25:19, 25:16, 25:17) |
| 24.10.2021 | 14:00 | PTSV Aachen II | TSV Germania Windeck | 3:1 (25:22, 11:25, 25:21, 25:20) |
| 24.10.2021 | 14:00 | FCJ Köln II | Dürener TV II | 0:3 (12:25, 20:25, 18:25) |
| 27.10.2021 | 20:00 | Brühler TV | TVA Hürth Volleyball II | 3:2 (25:15, 17:25, 21:25, 25:19, 15:12) |
| 30.10.2021 | 16:00 | TSV Germania Windeck | Dürener TV II | 3:0 (25:21, 25:21, 25:22) |
| 30.10.2021 | 19:00 | PTSV Aachen II | Brühler TV | 1:3 (21:25, 21:25, 25:21, 19:25) |
| 31.10.2021 | 16:00 | SSF Fortuna Bonn | FCJ Köln II | 3:1 (25:23, 25:19, 13:25, 25:18) |
| 31.10.2021 | 18:00 | Dürener TV II | TVA Hürth Volleyball II | 3:2 (15:25, 28:26, 28:26, 17:25, 15:12) |
| 13.11.2021 | 16:00 | FCJ Köln II | PTSV Aachen II | 3:1 (18:25, 25:20, 25:15, 25:18) |
| 14.11.2021 | 14:00 | PTSV Aachen II | TVA Hürth Volleyball II | 3:0 (25:23, 25:16, 25:21) |
| 14.11.2021 | 16:00 | TSV Germania Windeck | Brühler TV | 2:3 (25:21, 23:25, 19:25, 26:24, 9:15) |
| 14.11.2021 | 16:00 | Dürener TV II | SSF Fortuna Bonn | 3:2 (22:25, 25:23, 24:26, 25:14, 15:6) |
| 18.11.2021 | 20:15 | TVA Hürth Volleyball II | TSV Germania Windeck | 3:1 (23:25, 25:23, 25:17, 25:22) |
| 20.11.2021 | 16:00 | TVA Hürth Volleyball II | SSF Fortuna Bonn | 0:3 (25:27, 23:25, 21:25) |
| 20.11.2021 | 19:00 | Brühler TV | FCJ Köln II | 3:0 (25:17, 26:24, 25:18) |
| 20.11.2021 | 20:00 | PTSV Aachen II | Dürener TV II | 3:0 (25:20, 25:17, 28:26) |
| 21.11.2021 | 13:00 | FCJ Köln II | TVA Hürth Volleyball II | 3:0 (25:17, 27:25, 25:15) |
| 21.11.2021 | 18:00 | SSF Fortuna Bonn | TSV Germania Windeck | 0:3 (17:25, 17:25, 21:25) |
| 27.11.2021 | 16:00 | PTSV Aachen II | SSF Fortuna Bonn | 3:2 (25:18, 22:25, 23:25, 25:21, 15:13) |
| 27.11.2021 | 19:00 | FCJ Köln II | TSV Germania Windeck | 0:3 (0:25, 0:25, 0:25) |
| 27.11.2021 | 19:00 | TVA Hürth Volleyball II | Brühler TV | 0:3 (13:25, 28:30, 18:25) |
| 28.11.2021 | 17:00 | Brühler TV | Dürener TV II | 3:1 (25:19, 25:21, 23:25, 25:8) |
| 11.12.2021 | 16:00 | TVA Hürth Volleyball II | Dürener TV II | 3:0 (27:25, 25:22, 25:21) |
| 12.12.2021 | 16:00 | TSV Germania Windeck | PTSV Aachen II | 1:3 (25:22, 17:25, 22:25, 18:25) |
| 12.12.2021 | 16:00 | Dürener TV II | FCJ Köln II | 3:2 (25:19, 24:26, 21:25, 25:22, 15:11) |
| 12.12.2021 | 16:00 | SSF Fortuna Bonn | Brühler TV | 1:3 (6:25, 25:21, 21:25, 20:25) |
| 18.12.2021 | 16:00 | TVA Hürth Volleyball II | FCJ Köln II | 0:3 (0:25, 0:25, 0:25) |
| 18.12.2021 | 18:00 | Dürener TV II | TSV Germania Windeck | 3:0 (25:22, 25:23, 25:18) |
| 19.12.2021 | 16:00 | FCJ Köln II | SSF Fortuna Bonn | 3:1 (25:21, 21:25, 25:15, 25:15) |
| 19.12.2021 | 16:00 | TSV Germania Windeck | TVA Hürth Volleyball II | 2:3 (25:19, 25:14, 18:25, 20:25, 11:15) |
| 19.12.2021 | 17:00 | Brühler TV | PTSV Aachen II | 3:0 (25:19, 25:18, 25:12) |
| 08.01.2022 | 19:00 | SSF Fortuna Bonn | Dürener TV II | 3:1 (25:22, 25:18, 17:25, 25:11) |
| 08.01.2022 | 19:00 | TVA Hürth Volleyball II | PTSV Aachen II | 3:2 (15:25, 25:20, 21:25, 25:23, 15:5) |
| 09.01.2022 | 14:00 | PTSV Aachen II | FCJ Köln II | 1:3 (23:25, 22:25, 25:22, 15:25) |
| 09.01.2022 | 17:00 | Brühler TV | TSV Germania Windeck | 3:0 (25:22, 25:21, 25:15) |
| 15.01.2022 | 16:00 | TSV Germania Windeck | SSF Fortuna Bonn | 3:2 (25:22, 14:25, 21:25, 25:21, 15:9) |
| 15.01.2022 | 18:00 | Dürener TV II | PTSV Aachen II | 0:3 (21:25, 12:25, 20:25) |
| 16.01.2022 | 15:30 | SSF Fortuna Bonn | TVA Hürth Volleyball II | 0:3 (22:25, 21:25, 20:25) |
| 16.01.2022 | 16:00 | FCJ Köln II | Brühler TV | 0:3 (25:27, 16:25, 27:29) |
